Endocannabinoids allow for receiver neurons to control just how much input they’re finding, plus they try this by sending retrograde indicators (endocannabinoids) again to overactive sender neurons. A few major good reasons. 1st, THC doesn’t communicate with CB1 receptors in exactly the same style as the human body’s normal endocannabinoids. https://stephenqiwku.blogoscience.com/39271426/medical-marijuana-no-further-a-mystery